consider to use alpha for more correct p_adjustment

sequencing facility is using it!

alpha the significance cutoff used for optimizing the independent filtering (by default 0.1). If the adjusted p-value cutoff (FDR) will be a value other than 0.1, alpha should be set to that value.

See https://github.com/mlesche/dsp/blob/master/dsp/r_scripts/deseq_report.r#L410